Fourth Vital

Fourth Vital is building the AI-native upstream kidney-risk infrastructure layer for earlier kidney-risk insight – before conventional labs, before symptoms, and while there is still time to act.

Our platform combines non-invasive biosensing with AI to translate a previously inaccessible physiological signal into actionable kidney-risk intelligence for clinicians, kidney care platforms, and health systems. We are focused not only on earlier visibility into kidney disease, but also on earlier visibility into progression.

Rather than replacing standard labs such as UACR/eGFR, Fourth Vital is designed to complement them with an earlier and more frequent physiological layer between episodic testing.

We are currently collecting real patient data with London Health Sciences Centre in Canada and advancing a software-first platform with global relevance.

Selected milestones:

• Live real-patient data collection with London Health Sciences Centre in Canada

• Patent-pending non-invasive sensing approach

• Advanced AI models informed by real clinical data

• Growing international interest from kidney clinics, platforms, and partners